Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.54 |
| ▸ | CHAT | P28329 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177963 | 0.77 | SNCA (0.75) | SNCACHATTTRFABP4CCNA2 | |
| SCHEMBL7089586 | 0.76 | TTR (0.56) | SNCACHATTTRCDK2NR4A1 | |
| SCHEMBL3194355 | 0.76 | AURKA (0.57) | SNCACHATTTRCDK2NR4A1 | |
| SCHEMBL28865539 | 0.75 | TTR (0.54) | SNCACHATTTRFABP4CCNA2 | |
| SCHEMBL159399 | 0.73 | AURKA (0.75) | SNCACHATTTRFABP4CCNA2 | |
| SCHEMBL30822934 | 0.73 | AURKA (0.75) | SNCACHATTTRFABP4CCNA2 | |
| SCHEMBL11590263 | 0.73 | TTR (0.40) | SNCACHATTTRCASP6KDM4E | |
| SCHEMBL11429443 | 0.71 | AURKA (0.73) | SNCACHATTTRFABP4CCNA2 | |
| SCHEMBL3505111 | 0.71 | TTR (0.53) | SNCACHATTTRCDK2KDM4E | |
| SCHEMBL11759180 | 0.71 | AURKA (0.73) | SNCACHATTTRFABP4CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399674-A | Dyestuffs containing pyrimidine-carboxylic acid amide radical having fiber-reactive group, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | disclosed |