Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | FDPS | P14324 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TOP2A | P11388 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135932 | 0.95 | FDPS (0.63) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL8750886 | 0.95 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL9134282 | 0.91 | FDPS (0.63) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL9135722 | 0.89 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL9134299 | 0.87 | NFE2L2 (0.51) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL9136504 | 0.86 | FDPS (0.67) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL8750876 | 0.84 | FDPS (0.57) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL9133551 | 0.84 | FDPS (0.52) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL9136069 | 0.82 | TOP2A (0.55) | KDM4EALDH1A1SMN1; SMN2FDPSNFE2L2 | |
| Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411955 | 0.81 | FDPS (0.80) | KDM4EALDH1A1SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5426210-A | Water soluble sunscreen agents | SHISEIDO CO., LTD. (JP) | 1995-06-20 | — | — | US | disclosed |
| EP-0539601-A1 | CINNAMIC ACID/GLYCEROL ADDUCT, ULTRAVIOLET ABSORBER, AND DERMATOLOGIC PREPARATION | SHISEIDO COMPANY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |