Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 7/20 | 0.49 |
| ▸ | MDM4 | O15151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136558 | 1.00 | MDM2 (0.49) | MDM2MDM4TP53PTPN1CASP3 | |
| SCHEMBL5493695 | 0.89 | MDM2 (0.49) | MDM2MDM4TP53PTPN1CASP3 | |
| SCHEMBL8933064 | 0.88 | MDM2 (0.52) | MDM2MDM4TP53PTPN1CASP3 | |
| SCHEMBL9247661 | 0.88 | MDM2 (0.48) | MDM2MDM4TP53PTPN1CASP3 | |
| SCHEMBL7868739 | 0.86 | MDM4 (0.49) | MDM2MDM4TP53CASP3 | |
| SCHEMBL9545907 | 0.86 | MDM4 (0.49) | MDM2MDM4TP53CASP3 | |
| SCHEMBL9164727 | 0.86 | MDM4 (0.49) | MDM2MDM4TP53CASP3 | |
| SCHEMBL3725047 | 0.86 | MDM4 (0.55) | MDM2MDM4TP53PTPN1CASP3 | |
| SCHEMBL3724885 | 0.86 | MDM2 (0.59) | MDM2MDM4TP53PTPN1CASP3 | |
| SCHEMBL2304915 | 0.86 | MDM2 (0.59) | MDM2MDM4TP53PTPN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475129-A | Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1993025561-A1 | PHOSPHONOALKYL PHENYLALANINE COMPOUNDS SUITABLY PROTECTED FOR USE IN PEPTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-12-23 | — | — | WO | disclosed |
| US-5264607-A | Process of making benzylic α,α-diflurophosphonates from benzylic α-ketophosphorates | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-11-23 | — | — | US | disclosed |