SCHEMBL9545907

SCHEMBL9545907

CC(C)(C)OP(=O)(Cc1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1)OC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.49
TP53 P04637 3/20 0.49
MDM2 Q00987 6/20 0.46
CASP3 P42574 1/20 0.45
SLC17A5 Q9NRA2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9164727 1.00 MDM4 (0.49) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL7868739 1.00 MDM4 (0.49) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL2920917 0.88 MDM4 (0.50) MDM4TP53MDM2CASP3
SCHEMBL31011405 0.87 MDM4 (0.52) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL9545905 0.86 MDM4 (0.47) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL9137271 0.86 MDM4 (0.47) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL9137272 0.86 MDM4 (0.47) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL9136556 0.86 MDM2 (0.49) MDM4TP53MDM2CASP3
SCHEMBL9136558 0.86 MDM2 (0.49) MDM4TP53MDM2CASP3
SCHEMBL29842986 0.86 MDM4 (0.54) MDM4TP53MDM2CASP3SLC17A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993025561-A1 PHOSPHONOALKYL PHENYLALANINE COMPOUNDS SUITABLY PROTECTED FOR USE IN PEPTIDE SYNTHESIS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-12-23 WO claimed
CN-118271361-A Preparation method of phosphoric amino acid 晗海(南通)生物科技有限公司 2024-07-02 CN disclosed