Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.53 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.42 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602677 | 1.00 | ENPP2 (0.53) | ENPP2PHLPP2PTPN1SUMO2SUMO1 | |
| SCHEMBL8779873 | 0.90 | ENPP2 (0.51) | ENPP2PHLPP2PTPN1SUMO2SUMO1 | |
| SCHEMBL10341738 | 0.88 | ENPP2 (0.53) | ENPP2PHLPP2PTPN1SUMO2SUMO1 | |
| SCHEMBL10488474 | 0.86 | ENPP2 (0.51) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL10488468 | 0.86 | ENPP2 (0.51) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL10615183 | 0.85 | ENPP2 (0.62) | ENPP2PHLPP2PTPN1SUMO2SUMO1 | |
| SCHEMBL9135394 | 0.82 | ENPP2 (0.62) | ENPP2PHLPP2PTPN1SUMO2SUMO1 | |
| SCHEMBL7591240 | 0.82 | ENPP2 (0.70) | ENPP2PHLPP2PTPN1SUMO2SUMO1 | |
| SCHEMBL9626844 | 0.82 | ENPP2 (0.70) | ENPP2PHLPP2PTPN1SUMO2SUMO1 | |
| SCHEMBL10351176 | 0.82 | SENP3 (0.52) | ENPP2PHLPP2PTPN1SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399674-A | Dyestuffs containing pyrimidine-carboxylic acid amide radical having fiber-reactive group, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | disclosed |
| EP-0603595-A1 | Fibre reactive dyes, method for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-29 | — | — | EP | disclosed |
| US-5298607-A | Reactive dyes for cotton | CIBA-GEIGY CORPORATION (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0179549-B1 | WATER-SOLUBLE DYE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-11-23 | — | — | EP | disclosed |
| US-4808706-A | WET- AND LIGHFAST; SOLUBLE | CIBA-GEIGY CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0167219-B1 | FIBER-REACTIVE COMPOUND HAVING BOTH PYRIDINIOTRIAZINYL AND VINYLSULFONE TYPE GROUPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-28 | — | — | EP | disclosed |
| US-4680384-A | PYRIMIDINE DYES | CIBA-GEIGY CORPORATION (US) | 1987-07-14 | — | — | US | disclosed |
| US-4626589-A | Organic dye compound having both pyridiniotriazinyl and vinylsulfone type fiber-reactive groups | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-12-02 | — | — | US | disclosed |
| EP-0167219-A1 | Fiber-reactive compound having both pyridiniotriazinyl and vinylsulfone type groups | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-01-08 | — | — | EP | disclosed |
| US-4507236-A | Fibre-reactive dyes, containing both chloro and fluoro triazine radicals | CIBA-GEIGY CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| US-4263206-A | Reactive dyestuffs containing chlorine or fluorine substituents and one or more 1,3-dicyanobenzene radicals linked to the dyestuff at the 2-, 4- or 6-position | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| US-4261889-A | TRIAZINE DYES FOR COTTON | CIBA-GEIGY CORP. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4213899-A | FOR CELLULOSE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-07-22 | — | — | US | disclosed |
| US-4033944-A | Fibre-reactive hydroxycycloalkenyl-halo triazinyl containing dyestuffs | CIBA-GEIGY CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |