Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782533 | 1.00 | SLC6A2 (0.42) | SLC6A2HTR2AHTR2CSLC6A4HTR2B | |
| SCHEMBL8782674 | 1.00 | SLC6A2 (0.42) | SLC6A2HTR2AHTR2CSLC6A4HTR2B | |
| SCHEMBL9137150 | 1.00 | SLC6A2 (0.42) | SLC6A2HTR2AHTR2CSLC6A4HTR2B | |
| SCHEMBL8782526 | 1.00 | SLC6A2 (0.42) | SLC6A2HTR2AHTR2CSLC6A4HTR2B | |
| SCHEMBL3921318 | 0.86 | SLC6A3 (0.52) | SLC6A3 | |
| SCHEMBL1944023 | 0.86 | SLC6A3 (0.52) | SLC6A3 | |
| SCHEMBL5593759 | 0.86 | SLC6A3 (0.52) | SLC6A3 | |
| SCHEMBL1944024 | 0.86 | SLC6A3 (0.52) | SLC6A3 | |
| SCHEMBL7679057 | 0.86 | SLC6A3 (0.52) | SLC6A3 | |
| SCHEMBL5593754 | 0.86 | SLC6A3 (0.52) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407946-A | Pyrrolidine compounds which are useful as thromboxane AZ-inhibitors | ADIR ET COMPAGNIE (FR) | 1995-04-18 | — | — | US | disclosed |
| US-5387591-A | Possesses antithromboxane A2 properties; useful in treatment and prevention of thrombotic diseases | ADIR ET COMPAGNIE (FR) | 1995-02-07 | — | — | US | disclosed |