SCHEMBL5593759

SCHEMBL5593759

CN1CC[C@H](c2ccc(F)cc2)[C@H](CO)C1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3921318 1.00 SLC6A3 (0.52) SLC6A3
SCHEMBL1944024 1.00 SLC6A3 (0.52) SLC6A3
SCHEMBL5593754 1.00 SLC6A3 (0.52) SLC6A3
SCHEMBL7679057 1.00 SLC6A3 (0.52) SLC6A3
SCHEMBL13961124 1.00 SLC6A3 (0.52) SLC6A3
SCHEMBL12538468 1.00 SLC6A3 (0.52) SLC6A3
SCHEMBL1944023 1.00 SLC6A3 (0.52) SLC6A3
Hydrochloric Acid SCHEMBL10600725 0.98 SLC6A3 (0.51) SLC6A3
Hydrochloric Acid SCHEMBL10600718 0.98 SLC6A3 (0.51) SLC6A3
Hydrochloric Acid SCHEMBL10600732 0.98 SLC6A3 (0.51) SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022269643-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF INTERMEDIATE FOR PAROXETINE VIHITA CHEM PRIVATE LIMITED (IN) 2022-12-29 WO disclosed
WO-2007034270-A2 IMPROVED PROCESS FOR THE PREPARATION OF (-) TRANS-N-METHYL PAROXETINE ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) 2007-03-29 WO disclosed
US-6777554-B2 REACTING SESAMOL-TETRABUTYLAMMONIUM SALT WITH 4-(4-FLUOROPHENYL)-3-CHLOROMETHYL-N-METHYL-PIPERIDINE TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2004-08-17 US disclosed
US-20020151567-A1 Preparation of N-methylparoxetine and related intermediate compounds TEVA PHARMACEUTICAL INDUSTRIES LTD. (IR) 2002-10-17 US disclosed
EP-0152273-B1 A PHENYLPIPERIDINE DERIVATIVE, AND ITS SALTS, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM, AND THEIR THERAPEUTIC USE A/S FERROSAN (DK) 1989-09-06 EP disclosed
US-4593036-A (-)-Trans-4-(4-fluorophenyl)-3-[(4-methoxyphenoxy)methyl]-1-methylpiperidine useful as 5-HT potentiator A/S FERROSAN (DK) 1986-06-03 US disclosed
US-4585777-A 5-HYDROXYTRYPTAMINE A/S FERROSAN (DK) 1986-04-29 US disclosed
EP-0152273-A2 A phenylpiperidine derivative, and its salts, their preparation, compositions containing them, and their therapeutic use A/S FERROSAN (DK) 1985-08-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151567-A1 Preparation of N-methylparoxetine and related intermediate compounds PNMT, INMT, SLC6A4 SLC6A3 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.