SCHEMBL9137488

SCHEMBL9137488

O=C(OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9135973 1.00 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL29141572 1.00 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL6561516 1.00 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL9116861 1.00 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL9116724 1.00 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL11205486 0.90 THRB (0.33) THRB
SCHEMBL5915191 0.86 THRB (0.38) THRB
SCHEMBL5915218 0.84 THRB (0.50) THRBCA1CA2MMP1MMP2
SCHEMBL717932 0.80 THRB (0.44) THRBCA1CA2MMP1MMP2
SCHEMBL718350 0.80 THRB (0.44) THRBCA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5399718-A Direct fluorination process for making perfluorinated organic substances MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-21 US claimed
EP-0609200-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-08-10 EP claimed
WO-1990006296-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-14 WO claimed
US-5399718-A Direct fluorination process for making perfluorinated organic substances MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-21 US disclosed
US-5362919-A Direct fluorination process for making perfluorinated organic substances MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-11-08 US disclosed
EP-0609200-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-08-10 EP disclosed
US-5034525-A Fluoropolyethercarbonyltriamino derivatives of triazines DEKURA TAKATERU (JP) 1991-07-23 US disclosed
WO-1990006296-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-14 WO disclosed
US-4898683-A CORROSION RESISTANCE, ADHESION TO METALS DEKURA TAKATERU (JP) 1990-02-06 US disclosed