Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975118 | 0.89 | SRD5A2 (0.83) | SRD5A2LMNAGAAL3MBTL1MAPK1 | |
| SCHEMBL10723714 | 0.89 | SRD5A2 (0.83) | SRD5A2LMNAGAAL3MBTL1MAPK1 | |
| SCHEMBL1362 | 0.85 | ALDH1A1 (0.56) | LMNAL3MBTL1MAPK1CES1TDP1 | |
| SCHEMBL8764904 | 0.85 | ALDH1A1 (0.56) | LMNAL3MBTL1MAPK1CES1TDP1 | |
| SCHEMBL28914440 | 0.83 | MAPK1 (0.85) | SRD5A2LMNAGAAL3MBTL1MAPK1 | |
| SCHEMBL9798096 | 0.83 | CES2 (0.62) | LMNACES1TDP1ALDH1A1MAPT | |
| SCHEMBL8934653 | 0.83 | ALDH1A1 (0.54) | LMNAL3MBTL1MAPK1CES1TDP1 | |
| SCHEMBL9804074 | 0.83 | ALDH1A1 (0.54) | LMNAL3MBTL1MAPK1CES1TDP1 | |
| SCHEMBL7143035 | 0.83 | ALDH1A1 (0.54) | LMNAL3MBTL1MAPK1CES1TDP1 | |
| Potassium Ion SCHEMBL7143040 | 0.83 | ALDH1A1 (0.54) | LMNAL3MBTL1MAPK1CES1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464912-A | Adduct with rodlike mesogenic moiety, adduct made by reacting polyepoxide with nitro/so/ compound having epoxy-reactive hydrogen; conversion of hydroxyl product to ether, ester, halide, urethane, ketone, alkane; reducing nitro/so/ to amine | THE DOW CHEMICAL COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| US-5412044-A | Nitro group terminated mesogenic epoxy resin adducts | THE DOW CHEMICAL COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| US-5344898-A | Curable composition with stilbene groups and molecular orientation | THE DOW CHEMICAL COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5298575-A | Consists of at least one compound having more than one vicinal epoxide group and at least one amine terminated adduct containing one or more mesogenic moities | THE DOW CHEMICAL COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| US-4996347-A | Anticoagulant | FOURNIER INNOVATION ET SYNERGIE (FR) | 1991-02-26 | — | — | US | disclosed |
| US-4877808-A | ANTITHROMBOTICS | FOURNIER INNOVATION ET SYNERGIE (FR) | 1989-10-31 | — | — | US | disclosed |