Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906187 | 0.81 | ATM (0.55) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL9173368 | 0.81 | POLB (0.56) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL27478528 | 0.78 | ATM (0.55) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL19304523 | 0.78 | HPRT1 (0.61) | ATMALDH1A1POLBGAARAB9A | |
| SCHEMBL5288742 | 0.78 | HPRT1 (0.61) | ALDH1A1POLBGAARAB9AL3MBTL1 | |
| SCHEMBL13921739 | 0.78 | ALDH1A1 (0.53) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL20181454 | 0.77 | HPRT1 (0.48) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL12621364 | 0.77 | ATM (0.50) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL8724389 | 0.77 | ATM (0.63) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL12666720 | 0.77 | ATM (0.63) | ATMALDH1A1THRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475129-A | Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1993025561-A1 | PHOSPHONOALKYL PHENYLALANINE COMPOUNDS SUITABLY PROTECTED FOR USE IN PEPTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-12-23 | — | — | WO | disclosed |
| US-5264607-A | Process of making benzylic α,α-diflurophosphonates from benzylic α-ketophosphorates | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-11-23 | — | — | US | disclosed |