Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | CA2 | P00918 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 4/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | PPIB | P23284 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 1/20 | 0.32 |
| ▸ | PPID | Q08752 | 1/20 | 0.32 |
| ▸ | PPIG | Q13427 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137645 | 0.87 | MAOB (0.44) | MAOBALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL3748687 | 0.87 | NR1D1 (0.36) | CA1CA2CA4PPIBPPIA | |
| SCHEMBL12963768 | 0.84 | LMNA (0.43) | CA1CA2ALDH1A1NPC1RAB9A | |
| SCHEMBL25983031 | 0.83 | TOP2A (0.33) | MAOBALDH1A1PPIBPPIAPPID | |
| SCHEMBL29395464 | 0.82 | TDP1 (0.39) | CA1CA2CA4TSHRLMNA | |
| SCHEMBL189879 | 0.82 | TDP1 (0.39) | CA1CA2CA4TSHRLMNA | |
| SCHEMBL21652462 | 0.82 | TDP1 (0.39) | CA1CA2CA4TSHRLMNA | |
| SCHEMBL12761956 | 0.82 | NR1D1 (0.34) | ALDH1A1PPIBPPIAPPIDPPIG | |
| SCHEMBL12343945 | 0.82 | MAOB (0.32) | MAOBALDH1A1GAAGFERCYP2C19 | |
| SCHEMBL21652507 | 0.81 | MAOB (0.35) | MAOBCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5412148-A | Amplifier molecules derived from diethylene triaminepentaacetic acid for enhancement of diagnosis and therapy | THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 1995-05-02 | — | — | US | disclosed |
| US-5252317-A | Amplifier molecules for diagnosis and therapy derived from 3,5-bis[1-(3-amino-2,2-bis (aminomethyl)-propyl) oxymethyl] benzoic acid | THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 1993-10-12 | — | — | US | disclosed |
| US-5135737-A | Amplifier molecules for enhancement of diagnosis and therapy | THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 1992-08-04 | — | — | US | disclosed |