Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Itaconate SCHEMBL11290331 | 0.82 | HSD17B10 (0.49) | ALOX15HSD17B10ALDH1A1TP53CYP3A4 | |
| Itaconate SCHEMBL9136633 | 0.82 | HSD17B10 (0.49) | ALOX15HSD17B10ALDH1A1TP53CYP3A4 | |
| Itaconate SCHEMBL28357869 | 0.81 | ALOX15 (0.55) | ALOX15HSD17B10ALDH1A1TSHR | |
| Methacrylic Acid SCHEMBL9137100 | 0.80 | ALDH1A1 (0.44) | HSD17B10ALDH1A1TP53CYP3A4MAPK1 | |
| Ethyl Fumarate SCHEMBL9138192 | 0.80 | HCAR2 (0.46) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Itaconate SCHEMBL6467197 | 0.78 | ALOX15 (0.58) | ALOX15HSD17B10ALDH1A1TP53TSHR | |
| Itaconate SCHEMBL6247056 | 0.78 | TSHR (0.56) | ALOX15HSD17B10ALDH1A1TP53CYP3A4 | |
| SCHEMBL21219459 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRTHRB | |
| SCHEMBL6048095 | 0.77 | ALDH1A1 (0.39) | HSD17B10ALDH1A1TP53CYP3A4MAPK1 | |
| Itaconate SCHEMBL15419775 | 0.77 | ALDH1A1 (0.62) | ALOX15HSD17B10ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410005-A | Comprising acrylic amide and ester copolymers and their salts, having carboxyl and sulfonic acid groups as well as fluoro | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0583918-A2 | Reflection preventing film and process for forming resist pattern using the same | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-02-23 | — | — | EP | disclosed |