Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138701 | 0.89 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL9256165 | 0.84 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9393525 | 0.79 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL9393536 | 0.79 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL9135113 | 0.78 | ALOX5 (0.80) | ALOX5 | |
| Zd-2138 SCHEMBL29372755 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| Zd-2138 SCHEMBL1083603 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9216159 | 0.77 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL9136252 | 0.77 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9219847 | 0.77 | ALOX5 (0.79) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459271-A | Arylbicyclooctanes as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1995-10-17 | — | — | US | disclosed |