Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.50 |
| ▸ | MAOB | P27338 | 6/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139202 | 1.00 | MAOA (0.50) | MAOAMAOBCES2ALDH1A1LMNA | |
| SCHEMBL9139207 | 1.00 | MAOA (0.50) | MAOAMAOBCES2ALDH1A1LMNA | |
| SCHEMBL9138240 | 1.00 | MAOA (0.50) | MAOAMAOBCES2ALDH1A1LMNA | |
| SCHEMBL9138244 | 1.00 | MAOA (0.50) | MAOAMAOBCES2ALDH1A1LMNA | |
| SCHEMBL7606551 | 0.84 | CES2 (0.49) | MAOAMAOBCES2ALDH1A1LMNA | |
| SCHEMBL4488117 | 0.81 | MAOA (0.53) | MAOAMAOBCES2ALDH1A1LMNA | |
| SCHEMBL16870423 | 0.79 | MAOA (0.45) | MAOAMAOBALDH1A1 | |
| SCHEMBL16870532 | 0.79 | MAOA (0.45) | MAOAMAOBALDH1A1 | |
| SCHEMBL18205608 | 0.79 | MAOA (0.45) | MAOAMAOBALDH1A1 | |
| SCHEMBL18205655 | 0.79 | MAOA (0.45) | MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428002-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0447506-B1 | PYRIMIDINE AND TRIAZINE DERIVATIVES WITH HERBICIDAL AND PLANT GROWTH REGULATING PROPERTIES | CIBA GEIGY AG (CH) | 1994-10-26 | — | — | EP | disclosed |
| US-5332717-A | Herbicides, plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1994-07-26 | — | — | US | disclosed |