Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138388 | 1.00 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9136470 | 0.91 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9136465 | 0.91 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9298365 | 0.86 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9135768 | 0.86 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9138345 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9138489 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9138356 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL21 | 0.82 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL9138189 | 0.80 | AGTR1 (0.63) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389661-A | Treats hypertension, heart failure, glaucoma and hyperaldosteronism | WARNER-LAMBERT COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
| US-5322950-A | Treating hypertension, hyperaldosteronism, glaucoma, heart failure | WARNER-LAMBERT COMPANY (US) | 1994-06-21 | — | — | US | disclosed |