Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | P4HTM | Q9NXG6 | 7/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138961 | 0.92 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2P4HTM | |
| SCHEMBL9138754 | 0.91 | P4HTM (0.63) | MAPTNPC1RAB9AP4HTMPPARA | |
| SCHEMBL9144510 | 0.91 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2P4HTM | |
| SCHEMBL9143984 | 0.91 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2P4HTM | |
| SCHEMBL8870251 | 0.90 | NPC1 (0.52) | MAPTNPC1RAB9ASMN1; SMN2P4HTM | |
| SCHEMBL9140179 | 0.89 | MAPT (0.56) | MAPTNPC1RAB9ASMN1; SMN2P4HTM | |
| SCHEMBL9144504 | 0.88 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2P4HTM | |
| SCHEMBL9139467 | 0.88 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2P4HTM | |
| SCHEMBL9139136 | 0.88 | P4HTM (0.69) | MAPTNPC1RAB9ASMN1; SMN2P4HTM | |
| SCHEMBL8869525 | 0.88 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |