Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139877 | 0.92 | P4HTM (0.63) | P4HTMKMT2AMEN1MAPTRAB9A | |
| SCHEMBL9138404 | 0.91 | MAPT (0.57) | P4HTMKMT2AMEN1MAPTRAB9A | |
| SCHEMBL8869989 | 0.91 | P4HTM (0.59) | P4HTMKMT2AMEN1MAPTRAB9A | |
| SCHEMBL8868352 | 0.91 | P4HTM (0.61) | P4HTMKMT2AMEN1MAPTRAB9A | |
| SCHEMBL9140053 | 0.90 | AKR1C3 (0.57) | P4HTMKMT2AMEN1MAPTRAB9A | |
| SCHEMBL9143030 | 0.90 | P4HTM (0.60) | P4HTMKMT2AMEN1MAPTRAB9A | |
| SCHEMBL9139136 | 0.89 | P4HTM (0.69) | P4HTMKMT2AMEN1MAPTRAB9A | |
| SCHEMBL8868766 | 0.89 | P4HTM (0.59) | P4HTMKMT2AMEN1MAPTRAB9A | |
| SCHEMBL9136987 | 0.89 | CA1 (0.62) | P4HTMKMT2AMEN1MAPTRAB9A | |
| SCHEMBL9140542 | 0.89 | P4HTM (0.59) | P4HTMKMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |