Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359202 | 0.79 | NLRP3 (0.56) | NLRP3MAPK1SMN1; SMN2 | |
| SCHEMBL20702692 | 0.75 | NLRP3 (1.00) | NLRP3MAPK1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL11112611 | 0.75 | TSHR (0.47) | KMT2ALMNAMEN1 | |
| SCHEMBL9723445 | 0.73 | LPAR1 (0.52) | NLRP3SMN1; SMN2KMT2ALMNALPAR1 | |
| SCHEMBL8819874 | 0.72 | KMT2A (0.61) | NLRP3SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL9843936 | 0.72 | SMN1; SMN2 (0.77) | NLRP3SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL19853203 | 0.72 | NLRP3 (0.55) | NLRP3MAPK1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL9723542 | 0.72 | NLRP3 (0.55) | NLRP3MAPK1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL6429941 | 0.71 | KMT2A (0.65) | NLRP3SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL462304 | 0.71 | LPAR1 (0.66) | NLRP3SMN1; SMN2KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5384328-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1995-01-24 | — | — | US | disclosed |