Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.51 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137374 | 0.94 | NLRP3 (0.56) | NLRP3HDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL8867501 | 0.94 | NLRP3 (0.56) | NLRP3HDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL8869920 | 0.93 | NLRP3 (0.56) | NLRP3HDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL9141573 | 0.92 | NLRP3 (0.68) | NLRP3ALDH1A1LMNAABCC9ABCC8 | |
| SCHEMBL8867910 | 0.91 | NLRP3 (0.54) | NLRP3HDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL9018031 | 0.87 | NLRP3 (0.57) | NLRP3HDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL9143635 | 0.87 | P4HTM (0.58) | ALDH1A1LMNASMN1; SMN2P4HTMMEN1 | |
| SCHEMBL9139929 | 0.86 | NLRP3 (0.48) | NLRP3HDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL9139795 | 0.85 | NLRP3 (0.68) | NLRP3ALDH1A1LMNAABCC9ABCC8 | |
| SCHEMBL8869087 | 0.85 | NLRP3 (0.68) | NLRP3ALDH1A1LMNAABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |