Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805572 | 0.94 | TDP1 (0.42) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL8781804 | 0.91 | TDP1 (0.42) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL7805543 | 0.91 | TDP1 (0.43) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL9137735 | 0.90 | CCR5 (0.43) | TDP1ATMCCR5RAB9AALDH1A1 | |
| SCHEMBL8781845 | 0.90 | CCR5 (0.40) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL7858569 | 0.88 | TDP1 (0.41) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL9363174 | 0.87 | CCR5 (0.42) | TDP1ATMCCR5 | |
| SCHEMBL8782026 | 0.87 | CCR5 (0.39) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL7811544 | 0.87 | CCR5 (0.41) | TDP1ATMCCR5RAB9ANPC1 | |
| SCHEMBL9519179 | 0.86 | TDP1 (0.42) | TDP1ATMCCR5RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449672-A | Bactericides | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0544307-A1 | Alkylaminoakylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |