Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139486 | 0.92 | P4HTM (0.46) | P4HTMKMT2AALDH1A1GAABCL2L1 | |
| SCHEMBL9137443 | 0.89 | P4HTM (0.48) | P4HTMKMT2AALDH1A1GAABCL2L1 | |
| SCHEMBL9137990 | 0.89 | P4HTM (0.51) | P4HTMKMT2AALDH1A1GAABCL2L1 | |
| SCHEMBL9139225 | 0.89 | P4HTM (0.49) | P4HTMKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL9140268 | 0.88 | P4HTM (0.52) | P4HTMKMT2ABCL2L1MCL1MEN1 | |
| SCHEMBL9018123 | 0.88 | OPRM1 (0.43) | P4HTMKMT2AALDH1A1HPGDBCL2L1 | |
| SCHEMBL9139789 | 0.87 | P4HTM (0.57) | P4HTMKMT2AALDH1A1HPGDCA2 | |
| SCHEMBL9138015 | 0.86 | P4HTM (0.53) | P4HTMKMT2AALDH1A1CA5ACA2 | |
| SCHEMBL9139317 | 0.85 | P4HTM (0.55) | P4HTMKMT2AALDH1A1BCL2L1MCL1 | |
| SCHEMBL9139097 | 0.85 | BCL2L1 (0.55) | P4HTMGAABCL2L1MCL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |