Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139317 | 0.93 | P4HTM (0.55) | P4HTMALDH1A1MAPTSGMS1MEN1 | |
| SCHEMBL9140688 | 0.91 | PTPN1 (0.56) | P4HTMALDH1A1MAPTSGMS1CYP1A2 | |
| SCHEMBL9144421 | 0.89 | P4HTM (0.52) | P4HTMALDH1A1CA1CA2CA12 | |
| SCHEMBL9138662 | 0.88 | P4HTM (0.49) | P4HTMALDH1A1CA1CA2CA12 | |
| SCHEMBL9018076 | 0.88 | ALDH1A1 (0.49) | P4HTMALDH1A1CA1CA2CA12 | |
| SCHEMBL9137443 | 0.87 | P4HTM (0.48) | P4HTMALDH1A1MEN1KMT2A | |
| SCHEMBL9139930 | 0.87 | P4HTM (0.48) | P4HTMALDH1A1CA1CA2CA12 | |
| SCHEMBL9137990 | 0.87 | P4HTM (0.51) | P4HTMALDH1A1CA1CA2CA12 | |
| SCHEMBL9138982 | 0.86 | P4HTM (0.47) | P4HTMALDH1A1CA2MEN1KMT2A | |
| SCHEMBL9140268 | 0.86 | P4HTM (0.52) | P4HTMMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |