Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7330036 | 0.99 | L3MBTL1 (0.56) | L3MBTL1SLC18A3DRD2SIGMAR1MEN1 | |
| Hydrochloric Acid SCHEMBL7323236 | 0.91 | SIGMAR1 (0.58) | L3MBTL1SLC18A3DRD2SIGMAR1MEN1 | |
| Hydrochloric Acid SCHEMBL7323559 | 0.79 | GRIN2B (0.71) | L3MBTL1SLC18A3DRD2SIGMAR1MEN1 | |
| Hydrochloric Acid SCHEMBL7326427 | 0.77 | L3MBTL1 (0.58) | L3MBTL1DRD2SIGMAR1MEN1CYP2D6 | |
| SCHEMBL9374358 | 0.74 | SIGMAR1 (0.81) | SLC18A3DRD2SIGMAR1MEN1TP53 | |
| SCHEMBL10360724 | 0.72 | SLC18A3 (0.69) | SLC18A3DRD2SIGMAR1MEN1TP53 | |
| SCHEMBL2400051 | 0.71 | L3MBTL1 (0.71) | L3MBTL1ATMGLSALDH1A1 | |
| Hydrochloric Acid SCHEMBL7318616 | 0.71 | L3MBTL1 (0.53) | L3MBTL1DRD2SIGMAR1CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9137258 | 0.71 | L3MBTL1 (0.50) | L3MBTL1DRD2SIGMAR1CYP3A4TSHR | |
| SCHEMBL27542888 | 0.71 | SIGMAR1 (0.66) | SLC18A3SIGMAR1MEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424312-A | Treating central nervous system disorders, high blood pressure | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |