Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142854 | 0.88 | P4HTM (0.60) | P4HTMKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9137568 | 0.88 | P4HTM (0.55) | P4HTMMAPK1HSD17B10ALDH1A1CA1 | |
| SCHEMBL9139942 | 0.86 | P4HTM (0.53) | P4HTMMAPK1ALDH1A1MAPTCA1 | |
| SCHEMBL8869176 | 0.85 | P4HTM (0.53) | P4HTMKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL9018519 | 0.84 | P4HTM (0.80) | P4HTMKDM4EMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL8869543 | 0.84 | P4HTM (0.76) | P4HTMKDM4EMAPK1EGFRL3MBTL1 | |
| SCHEMBL9138365 | 0.83 | LMNA (0.52) | P4HTMMAPK1MAPTTSHRLMNA | |
| SCHEMBL9143209 | 0.83 | RAB9A (0.57) | P4HTMALDH1A1MAPTHPGDCA1 | |
| SCHEMBL9138327 | 0.83 | PTPN1 (0.52) | P4HTMKDM4EALDH1A1MAPTCA1 | |
| SCHEMBL8868894 | 0.83 | P4HTM (0.51) | P4HTMKDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |