Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137797 | 0.90 | P4HTM (0.66) | P4HTMLMNA | |
| SCHEMBL9139554 | 0.89 | P4HTM (0.50) | P4HTMLMNASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9142854 | 0.88 | P4HTM (0.60) | P4HTMLMNASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9140800 | 0.86 | P4HTM (0.56) | P4HTM | |
| SCHEMBL9139748 | 0.86 | NPC1 (0.58) | P4HTMLMNASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9138954 | 0.86 | L3MBTL1 (0.48) | P4HTMLMNASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL9141583 | 0.86 | P4HTM (0.53) | P4HTMLMNAALDH1A1 | |
| SCHEMBL9137563 | 0.85 | P4HTM (0.52) | P4HTMMAPK1ALDH1A1NPC1RAB9A | |
| SCHEMBL9140269 | 0.84 | NPC1 (0.53) | P4HTMSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9139101 | 0.84 | NPC1 (0.53) | P4HTMLMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |