Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9143209 | 0.90 | RAB9A (0.57) | P4HTMHDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL9138954 | 0.90 | L3MBTL1 (0.48) | P4HTMHDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL9139742 | 0.89 | P4HTM (0.54) | P4HTMNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL9139557 | 0.87 | P4HTM (0.52) | P4HTMHDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL9139930 | 0.87 | P4HTM (0.48) | P4HTMNPC1RAB9ALMNABCL2L1 | |
| SCHEMBL9137797 | 0.87 | P4HTM (0.66) | P4HTMLMNA | |
| SCHEMBL9141583 | 0.84 | P4HTM (0.53) | P4HTMSCN3ALMNAALDH1A1CA12 | |
| SCHEMBL8868481 | 0.84 | HDAC3 (0.51) | P4HTMHDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL9140800 | 0.83 | P4HTM (0.56) | P4HTMBCL2L1MCL1 | |
| SCHEMBL9139101 | 0.83 | NPC1 (0.53) | P4HTMHDAC8HDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |