Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138872 | 0.94 | CYP3A4 (0.46) | LMNACYP3A4CYP2C9MAPTTSHR | |
| SCHEMBL9139834 | 0.93 | LMNA (0.49) | LMNACYP3A4CYP2C9MAPTTSHR | |
| SCHEMBL9139388 | 0.92 | CYP3A4 (0.50) | LMNACYP3A4CYP2C9MAPTTSHR | |
| SCHEMBL9138876 | 0.91 | LMNA (0.47) | LMNACYP3A4CYP2C9MAPTTSHR | |
| SCHEMBL9140390 | 0.89 | LMNA (0.42) | LMNACYP3A4CYP2C9MAPTTSHR | |
| SCHEMBL9137483 | 0.88 | P4HTM (0.52) | LMNACYP3A4CYP2C9MAPTTSHR | |
| SCHEMBL9018372 | 0.88 | LMNA (0.44) | LMNACYP3A4CYP2C9MAPTTSHR | |
| SCHEMBL9141455 | 0.87 | ALDH1A1 (0.49) | LMNACYP3A4CYP2C9MAPTTSHR | |
| SCHEMBL9140361 | 0.87 | MAPT (0.53) | LMNACYP3A4CYP2C9MAPTTSHR | |
| SCHEMBL9140379 | 0.87 | LMNA (0.42) | LMNACYP3A4CYP2C9MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |