SCHEMBL9140267

SCHEMBL9140267

CCCC[C](C)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.42
CES2 O00748 5/20 0.41
ALDH1A1 P00352 3/20 0.38
TP53 P04637 1/20 0.38
CA1 P00915 2/20 0.36
SPHK2 Q9NRA0 1/20 0.35
SPHK1 Q9NYA1 1/20 0.35
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
FAAH O00519 1/20 0.32
AKR1B1 P15121 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
THRB P10828 1/20 0.32
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL993689 0.92 SPHK2 (0.44) CES1CES2ALDH1A1SPHK2SPHK1
SCHEMBL28314327 0.89 SPHK2 (0.48) CES1CES2ALDH1A1SPHK2SPHK1
SCHEMBL28314586 0.89 SPHK2 (0.48) CES1CES2ALDH1A1SPHK2SPHK1
SCHEMBL28315556 0.89 SPHK2 (0.48) CES1CES2ALDH1A1SPHK2SPHK1
SCHEMBL4621531 0.81
SCHEMBL28494898 0.74 ALDH1A1 (0.42) CES1CES2ALDH1A1TP53CA1
SCHEMBL6104108 0.74 FAAH (0.46) CES1CES2ALDH1A1TP53FAAH
SCHEMBL11141897 0.74 CES1 (0.36) CES1CES2ALDH1A1TP53CA1
SCHEMBL10412145 0.73 CES1 (0.43) CES1CES2ALDH1A1TP53CA1
SCHEMBL27886605 0.72 CES1 (0.39) CES1CES2ALDH1A1TP53CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110172019-A The metal salt of malonic acid as the nucleating additive for crystalline thermoplastic 印度石油有限公司 2019-08-27 CN claimed
CN-110172019-A The metal salt of malonic acid as the nucleating additive for crystalline thermoplastic 印度石油有限公司 2019-08-27 CN disclosed
US-5389447-A Binders; dispersing agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-02-14 US disclosed
EP-0483175-A1 POLYMERS OF 2,2-DISUBSTITUTED-3-HYDROXYPROPIONIC ACID FOR CERAMIC PROCESSING E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-06 EP disclosed
WO-1990015784-A1 POLYMERS OF 2,2-DISUBSTITUTED-3-HYDROXYPROPIONIC ACID FOR CERAMIC PROCESSING E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-12-27 WO disclosed
EP-0086826-A4 ALPHA-BRANCHED ALKYLTHIOPHOSPHATE PESTICIDES. FMC CORP (US) 1983-12-23 EP disclosed
EP-0086826-A1 ALPHA-BRANCHED ALKYLTHIOPHOSPHATE PESTICIDES. FMC CORP (US) 1983-08-31 EP disclosed
WO-1983000870-A1 ALPHA-BRANCHED ALKYLTHIOPHOSPHATE PESTICIDES FMC CORP (US) 1983-03-17 WO disclosed