Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139411 | 0.95 | RAB9A (0.45) | P4HTMRAB9AFBP1KMT2AMEN1 | |
| SCHEMBL9139745 | 0.92 | P4HTM (0.47) | P4HTMRAB9ACASP3KMT2AMEN1 | |
| SCHEMBL9140303 | 0.90 | P4HTM (0.44) | P4HTMRAB9AFBP1CASP3KMT2A | |
| SCHEMBL8868688 | 0.89 | P4HTM (0.47) | P4HTMRAB9AFBP1CASP3KMT2A | |
| SCHEMBL8869265 | 0.89 | P4HTM (0.47) | P4HTMRAB9AFBP1CASP3KMT2A | |
| SCHEMBL9142109 | 0.89 | SMN1; SMN2 (0.47) | P4HTMFBP1CASP3KMT2AMEN1 | |
| SCHEMBL9139358 | 0.89 | P4HTM (0.50) | P4HTMCASP3BCL2L1MCL1 | |
| SCHEMBL9143465 | 0.89 | RAB9A (0.53) | P4HTMRAB9ACASP3NPC1BCL2L1 | |
| SCHEMBL9018346 | 0.88 | RAB9A (0.39) | P4HTMRAB9AFBP1CASP3KMT2A | |
| SCHEMBL9143301 | 0.88 | HPGD (0.45) | P4HTMRAB9AFBP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |