Sugi Predict

Sugi Predict / Compounds / SCHEMBL91406

SCHEMBL91406

SCHEMBL91406

Cc1ccc(OCCN(C)C)cc1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ HRH3 Q9Y5N1 3/20 0.66
▸ LTA4H P09960 2/20 0.63
▸ KEAP1 Q14145 1/20 0.63
▸ NFE2L2 Q16236 1/20 0.63
▸ KCNH2 Q12809 1/20 0.62
▸ KDM4E B2RXH2 2/20 0.57
▸ ALDH1A1 P00352 2/20 0.57
▸ SMN1; SMN2 Q16637 1/20 0.57
▸ ACHE P22303 1/20 0.52
▸ ESRRG P62508 1/20 0.52
▸ DRD2 P14416 1/20 0.52
▸ DRD4 P21917 1/20 0.52
▸ DRD3 P35462 1/20 0.52
▸ MAPT P10636 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020310 0.91 HRH3 (0.56) HRH3LTA4HKEAP1NFE2L2KCNH2
SCHEMBL8226392 0.89 KDM4E (0.71) HRH3LTA4HKEAP1NFE2L2KCNH2
SCHEMBL4618973 0.88 KDM4E (0.54) HRH3LTA4HKEAP1NFE2L2KCNH2
SCHEMBL22831328 0.87 KCNH2 (0.79) HRH3LTA4HKEAP1NFE2L2KCNH2
SCHEMBL12603035 0.86 KDM4E (0.70) HRH3KCNH2KDM4EALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL9256011 0.85 HRH3 (0.50) HRH3LTA4HKEAP1NFE2L2KCNH2
SCHEMBL23074664 0.83 KCNH2 (0.59) HRH3LTA4HKEAP1NFE2L2KCNH2
SCHEMBL15834787 0.83 KDM4E (0.60) HRH3LTA4HKEAP1NFE2L2KCNH2
SCHEMBL14922323 0.83 HRH3 (0.66) HRH3LTA4HKEAP1NFE2L2KCNH2
SCHEMBL14924417 0.82 KCNH2 (0.67) HRH3LTA4HKEAP1NFE2L2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115318256-A Anion exchange-hydrophobic mixed mode chromatography resin 生物辐射实验室股份有限公司 2022-11-11 — — CN claimed
CN-111818980-B Anion exchange-hydrophobic mixed mode chromatography resins 生物辐射实验室股份有限公司 2022-10-11 — — CN claimed
US-12582963-B2 Separation matrix and method of separation CYTIVA BIOPROCESS R&D AB (SE) 2026-03-24 — — US disclosed
US-12343702-B2 Anionic exchange-hydrophobic mixed mode chromatography resin BIO-RAD LABORATORIES, INC. (US) 2025-07-01 — — US disclosed
US-20250196100-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESIN BIO-RAD LABORATORIES, INC. 2025-06-19 — — US disclosed
EP-4142930-B1 SEPARATION MATRIX AND METHOD OF SEPARATION PURIDIFY LTD (GB) 2024-05-08 — — EP disclosed
WO-2023141432-A2 APOL1 INHIBITORS AND METHODS OF USE MAZE THERAPEUTICS, INC. (US) 2023-07-27 — — WO disclosed
US-20230191368-A1 Separation Matrix and Method of Separation CYTIVA BIOPROCESS R&D AB (SE) 2023-06-22 — — US disclosed
EP-4142930-A1 SEPARATION MATRIX AND METHOD OF SEPARATION PURIDIFY LTD. (GB) 2023-03-08 — — EP disclosed
US-11576891-B2 Methods of treating or preventing estrogen-related diseases ENDORECHERCHE, INC. 2023-02-14 — — US disclosed
WO-2022263548-A1 3-SUBSTITUTED 1H-PYRROLO[2,3-B]PYRIDINE AS GRK5 MODULATORS LEAD DISCOVERY CENTER GMBH (DE) 2022-12-22 — — WO disclosed
US-20070161677-A1 Bisarylurea derivatives MERCK PATENT GMBH (DE) 2007-07-12 — — US disclosed
US-7196080-B2 Respiratory system disordeers; chronic obstructive pulminary disease ASTELLAS PHARMA INC. (JP) 2007-03-27 — — US disclosed
US-7183409-B2 Basic mono- and bisazo compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2007-02-27 — — US disclosed
US-7183409-B2 Basic mono- and bisazo compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2007-02-27 — — US disclosed
US-20070010515-A1 [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-01-11 — — US disclosed
US-20070010515-A1 [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-01-11 — — US disclosed
WO-2006030032-A1 NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS JANSSEN PHARMACEUTICA N.V. (BE) 2006-03-23 — — WO disclosed
WO-2005087726-A1 NOVEL ARYL-CONTAINING 5-ACYLINDOLINONES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-09-22 — — WO disclosed
WO-2003020721-A1 PYRROLO PYRIMIDINES AS AGENTS FOR THE INHIBITION OF CYSTEIN PROTEASES NOVARTIS AG (CH) 2003-03-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161677-A1 Bisarylurea derivatives BRAF, RAF1, NRAS HRH3 2940/4885LTA4H 4652/4885KEAP1 938/4885
US-20070010515-A1 [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof HLA-C, TPMT, TAP1 HRH3 403/4885LTA4H 461/4885KEAP1 1618/4885
US-11576891-B2 Methods of treating or preventing estrogen-related diseases SHBG, ESRRA, ESR2 HRH3 1922/4885LTA4H 1161/4885KEAP1 1355/4885
US-20250196100-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESIN SLC7A1, ABCG2, MSR1 HRH3 6/4885LTA4H 1282/4885KEAP1 3946/4885
US-12582963-B2 Separation matrix and method of separation EPCAM, PA2G4, MAG HRH3 1754/4885LTA4H 2775/4885KEAP1 4329/4885
US-12343702-B2 Anionic exchange-hydrophobic mixed mode chromatography resin FCGRT, PBRM1, BCR HRH3 99/4885LTA4H 3846/4885KEAP1 3641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.