Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91406 | 0.88 | HRH3 (0.66) | KDM4EALDH1A1HRH3LTA4HKEAP1 | |
| SCHEMBL12570290 | 0.86 | DRD2 (0.57) | KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL12570286 | 0.86 | DRD2 (0.57) | KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL8675393 | 0.86 | DRD2 (0.57) | KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL4239666 | 0.86 | DRD2 (0.57) | KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL12570291 | 0.86 | DRD2 (0.57) | KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL15509555 | 0.83 | LTA4H (0.68) | KDM4EALDH1A1TDP1HRH3LTA4H | |
| SCHEMBL8226392 | 0.82 | KDM4E (0.71) | KDM4EALDH1A1HRH3LTA4HKEAP1 | |
| Hydrochloric Acid SCHEMBL5428138 | 0.81 | LTA4H (0.66) | KDM4EALDH1A1TDP1HRH3LTA4H | |
| SCHEMBL29316505 | 0.81 | DRD2 (0.48) | KDM4EALDH1A1TDP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1892235-A1 | Method for preparing arylpoly(oxyalkyl) amines | Dishman Pharmaceuticals & Chemicals Ltd. (IN) | 2008-02-27 | — | — | EP | disclosed |
| EP-1790695-A1 | Non-aqueous quinacridone dispersions using dispersion synergists | Agfa Graphics N.V. (BE) | 2007-05-30 | — | — | EP | disclosed |