Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868823 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1MAPTP4HTM | |
| SCHEMBL9136744 | 0.91 | ALDH1A1 (0.51) | SMN1; SMN2LMNAALDH1A1MAPTP4HTM | |
| SCHEMBL8868577 | 0.91 | P4HTM (0.53) | SMN1; SMN2LMNAALDH1A1MAPTP4HTM | |
| SCHEMBL9140771 | 0.90 | ALDH1A1 (0.49) | SMN1; SMN2LMNAALDH1A1MAPTP4HTM | |
| SCHEMBL8869039 | 0.89 | LMNA (0.53) | SMN1; SMN2LMNAALDH1A1MAPTP4HTM | |
| SCHEMBL9139317 | 0.89 | P4HTM (0.55) | SMN1; SMN2LMNAALDH1A1MAPTP4HTM | |
| SCHEMBL9018112 | 0.89 | LMNA (0.51) | SMN1; SMN2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL9140778 | 0.88 | KMT2A (0.51) | SMN1; SMN2LMNAALDH1A1MAPTP4HTM | |
| SCHEMBL8869766 | 0.88 | P4HTM (0.53) | SMN1; SMN2LMNAALDH1A1MAPTP4HTM | |
| SCHEMBL8868488 | 0.87 | LMNA (0.51) | SMN1; SMN2LMNAALDH1A1MAPTP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |