Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.54 |
| ▸ | PIM1 | P11309 | 2/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121706 | 0.76 | KMT2A (0.55) | HPGDPIM1PIM2CISD1 | |
| SCHEMBL9121700 | 0.76 | KMT2A (0.55) | HPGDPIM1PIM2CISD1 | |
| SCHEMBL9326976 | 0.75 | HPGD (0.80) | HPGDPIM1PIM2GPR35CISD1 | |
| SCHEMBL9326177 | 0.75 | HPGD (0.80) | HPGDPIM1PIM2GPR35CISD1 | |
| SCHEMBL10272939 | 0.75 | PIM1 (0.74) | HPGDPIM1PIM2GPR35CISD1 | |
| SCHEMBL30973657 | 0.75 | PIM1 (0.60) | HPGDPIM1PIM2GPR35CISD1 | |
| SCHEMBL14215984 | 0.75 | KMT2A (0.53) | HPGDPOLB | |
| SCHEMBL9570769 | 0.73 | PIM1 (0.71) | HPGDPIM1PIM2GPR35CISD1 | |
| SCHEMBL9570763 | 0.73 | PIM1 (0.71) | HPGDPIM1PIM2GPR35CISD1 | |
| SCHEMBL9803954 | 0.73 | PIM1 (0.74) | HPGDPIM1PIM2GPR35CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478850-A | Treating hyperglycemia, hyperlipidemia, hypertension | BEECHAM GROUP PLC (GB) | 1995-12-26 | — | — | US | disclosed |