Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ESRRA | P11474 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121706 | 1.00 | KMT2A (0.55) | KMT2AMEN1NPC1PIM1PIM2 | |
| SCHEMBL9121723 | 0.90 | KMT2A (0.54) | KMT2AMEN1NPC1HPGDLMNA | |
| SCHEMBL9123712 | 0.82 | KMT2A (0.64) | KMT2AMEN1NPC1HPGDLMNA | |
| SCHEMBL8458179 | 0.78 | KMT2A (0.55) | KMT2AMEN1NPC1HPGDLMNA | |
| SCHEMBL9121310 | 0.77 | KMT2A (0.53) | KMT2AMEN1NPC1HPGDLMNA | |
| SCHEMBL9141936 | 0.76 | HPGD (0.54) | PIM1PIM2CISD1HPGD | |
| SCHEMBL30973657 | 0.74 | PIM1 (0.60) | PIM1PIM2CISD1HPGD | |
| SCHEMBL7457209 | 0.73 | PIM1 (0.71) | PIM1PIM2HPGDIGF1RPDE4B | |
| SCHEMBL7457214 | 0.73 | PIM1 (0.71) | PIM1PIM2HPGDIGF1RPDE4B | |
| SCHEMBL2733862 | 0.72 | PIM1 (0.81) | NPC1PIM1PIM2CISD1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478851-A | Hyperglycemic agent and antilipemic agent | BEECHAM GROUP PLC (GB) | 1995-12-26 | — | — | US | claimed |
| EP-0555264-A1 | NOVEL COMPOUNDS | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | claimed |
| WO-1992007850-A1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | claimed |
| US-5478851-A | Hyperglycemic agent and antilipemic agent | BEECHAM GROUP PLC (GB) | 1995-12-26 | — | — | US | disclosed |
| EP-0555264-A1 | NOVEL COMPOUNDS | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007850-A1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | disclosed |