Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | HPGDS | O60760 | 1/20 | 0.62 |
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.49 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670732 | 0.82 | RECQL (0.71) | RECQLHPGDSGUSBNPY5RSMPD3 | |
| SCHEMBL9141786 | 0.81 | TRPV1 (0.51) | GUSBADORA1KITPDE4APDE4B | |
| SCHEMBL11226225 | 0.80 | GUSB (0.44) | RECQLHPGDSGUSBADORA1NPY5R | |
| SCHEMBL15614429 | 0.80 | RECQL (1.00) | RECQLHPGDSGUSBNPY5RSMPD3 | |
| SCHEMBL28868937 | 0.80 | RECQL (0.60) | RECQLHPGDSNPY5RSCN2ATNKS | |
| SCHEMBL2842992 | 0.76 | HPGDS (1.00) | RECQLHPGDSNPY5RSMPD3SCN2A | |
| Bromide SCHEMBL9143339 | 0.76 | GUSB (0.52) | RECQLGUSBADORA1NPY5RSCN2A | |
| SCHEMBL16007517 | 0.72 | GUSB (1.00) | GUSBCDK4CCND1TNKSTNKS2 | |
| SCHEMBL31238611 | 0.72 | GUSB (1.00) | GUSBCDK4CCND1TNKSTNKS2 | |
| SCHEMBL9564892 | 0.72 | EGLN1 (0.44) | RECQLNPY5RSCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438052-A | Cephalosporin derivatives | HOFFMANN-LA ROCHE INC. (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0544166-A2 | Cephalosporinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |