Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564754 | 0.82 | PTGS1 (0.39) | EGLN1PTGS1DGAT1GRIN2DGRIN3B | |
| SCHEMBL28868937 | 0.78 | RECQL (0.60) | PIN1RECQLCOMTNPY5RSCN2A | |
| Bromide SCHEMBL9143339 | 0.76 | GUSB (0.52) | PIN1RECQLCOMTNPY5RSCN2A | |
| SCHEMBL9564854 | 0.74 | ALDH1A1 (0.44) | PTGS1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5156156 | 0.73 | PTGS1 (0.59) | PTGS1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL9564959 | 0.72 | PTGS1 (0.40) | PTGS1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL9142152 | 0.72 | RECQL (0.66) | RECQLNPY5RSCN2A | |
| SCHEMBL9144177 | 0.69 | RECQL (0.48) | PIN1RECQLCOMTNPY5RSCN2A | |
| SCHEMBL9564901 | 0.69 | PTGS1 (0.42) | PTGS1DGAT1 | |
| SCHEMBL29678121 | 0.69 | RXRA (0.50) | PTGS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544166-A2 | Cephalosporinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |