Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146402 | 0.90 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL1887989 | 0.86 | AGTR1 (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL9030246 | 0.83 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9031569 | 0.79 | AGTR1 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL1895464 | 0.79 | AGTR1 (0.66) | AGTR1AGTR2PPARG | |
| SCHEMBL1896631 | 0.79 | AGTR1 (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL1895972 | 0.78 | AGTR1 (0.66) | AGTR1AGTR2PPARG | |
| SCHEMBL1893583 | 0.78 | AGTR1 (0.55) | AGTR1AGTR2PPARG | |
| SCHEMBL9142219 | 0.78 | ACHE (0.51) | AGTR1AGTR2PPARG | |
| SCHEMBL1897511 | 0.76 | AGTR1 (0.61) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411980-A | Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists | MERCK & CO., INC. (US) | 1995-05-02 | — | — | US | disclosed |