Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.58 |
| ▸ | PGR | P06401 | 9/20 | 0.58 |
| ▸ | AR | P10275 | 7/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737707 | 0.93 | NR3C1 (0.58) | NR3C1PGRARNR3C2ESR1 | |
| SCHEMBL8796336 | 0.91 | NR3C1 (0.70) | NR3C1PGRARNR3C2ESR1 | |
| SCHEMBL10400818 | 0.91 | PGR (0.59) | NR3C1PGRARNR3C2ESR1 | |
| SCHEMBL10889198 | 0.91 | PGR (0.59) | NR3C1PGRARNR3C2ESR1 | |
| SCHEMBL10400816 | 0.91 | PGR (0.59) | NR3C1PGRARNR3C2ESR1 | |
| SCHEMBL10888423 | 0.91 | NR3C1 (0.66) | NR3C1PGRARNR3C2ESR1 | |
| SCHEMBL10595675 | 0.90 | NR3C1 (0.68) | NR3C1PGRARNR3C2ESR1 | |
| SCHEMBL9148960 | 0.90 | NR3C1 (0.66) | NR3C1PGRARNR3C2ESR1 | |
| SCHEMBL10400824 | 0.90 | NR3C1 (0.68) | NR3C1PGRARNR3C2ESR1 | |
| SCHEMBL10400822 | 0.90 | NR3C1 (0.68) | NR3C1PGRARNR3C2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349481-B1 | 13-Alkyl-11-beta-phenyl gonanes | SCHERING AG (DE) | 1995-11-02 | — | — | EP | claimed |
| US-5446036-A | Contraceptive | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | claimed |
| EP-0349481-B1 | 13-Alkyl-11-beta-phenyl gonanes | SCHERING AG (DE) | 1995-11-02 | — | — | EP | disclosed |
| US-5446036-A | Contraceptive | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | disclosed |
| US-5273971-A | A 3-keto or 3-hydroxyimino-4,9-diene derivative | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |