Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAP2 | P11137 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535590 | 0.88 | KDM4E (0.58) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL9141585 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL2731047 | 0.77 | MAP2 (0.61) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL9144077 | 0.75 | TUBB4A (0.54) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL2351718 | 0.73 | MAP2 (0.48) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL9144716 | 0.73 | ICAM1 (0.56) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL15427780 | 0.72 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL15428085 | 0.71 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL15428075 | 0.71 | KDM4E (0.81) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL16711695 | 0.71 | KDM4E (0.70) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424329-A | Administering an antiinflammatory agent to prevent leukocytes bonding to vascular endothelium, treating rheumatoid arthritis , asthma, psoriasis and AIDS | WARNER-LAMBERT COMPANY (US) | 1995-06-13 | — | — | US | claimed |
| US-5424329-A | Administering an antiinflammatory agent to prevent leukocytes bonding to vascular endothelium, treating rheumatoid arthritis , asthma, psoriasis and AIDS | WARNER-LAMBERT COMPANY (US) | 1995-06-13 | — | — | US | disclosed |