Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146433 | 0.95 | AGTR1 (0.86) | AGTR1AGTR2 | |
| SCHEMBL9146382 | 0.91 | AGTR1 (0.83) | AGTR1AGTR2 | |
| SCHEMBL9148361 | 0.91 | — | — | |
| SCHEMBL9565988 | 0.91 | AGTR1 (0.79) | AGTR1AGTR2 | |
| SCHEMBL9565979 | 0.91 | AGTR1 (0.79) | AGTR1AGTR2 | |
| SCHEMBL9142437 | 0.90 | — | — | |
| SCHEMBL9565999 | 0.90 | AGTR1 (0.83) | AGTR1 | |
| SCHEMBL9373638 | 0.89 | AGTR2 (0.90) | AGTR1AGTR2 | |
| SCHEMBL9145885 | 0.88 | — | — | |
| SCHEMBL9143211 | 0.88 | AGTR2 (1.00) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411980-A | Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists | MERCK & CO., INC. (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0526001-A1 | Substituted triazolinones | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1993001177-A1 | SUBSTITUTED TRIAZOLINONES | MERCK & CO., INC. (US) | 1993-01-21 | — | — | WO | disclosed |