SCHEMBL9145303

SCHEMBL9145303

Cc1cccc2c1C=CC2[SiH2]C1C=Cc2c(C)cccc21.[LiH]

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.30
ATM Q13315 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8770349 0.98 TRPA1 (0.31) TRPA1ATMCYP1A2CYP2A6HTR2C
SCHEMBL9145318 0.96 TRPA1 (0.30) TRPA1ATMCYP1A2CYP2A6HTR2C
SCHEMBL9144838 0.87
SCHEMBL8770683 0.85 HTR2C (0.30) CYP1A2CYP2A6HTR2C
SCHEMBL9143001 0.83
SCHEMBL1025201 0.75 ALDH1A1 (0.36) TRPA1CYP1A2CYP2A6HTR2C
SCHEMBL9143901 0.74 ALDH1A1 (0.31) CYP1A2CYP2A6HTR2C
SCHEMBL16223674 0.74 ALDH1A1 (0.34) CYP1A2CYP2A6HTR2C
SCHEMBL5605209 0.73 HTR2C (0.31) CYP1A2CYP2A6HTR2C
SCHEMBL9145268 0.73 HTR2C (0.31) CYP1A2CYP2A6HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5391660-A Narrow molecular weight distribution by addition polymerizing a olefin or mixtures in a catalysts mixtures having metal compounds, halometal compound and alumoxanes NIPPON OIL COMPANY, LIMITED (JP) 1995-02-21 US disclosed