Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145398 | 1.00 | ADRB2 (0.47) | ADRB2TDP1HTTSTAT3KMT2A | |
| SCHEMBL2082380 | 0.91 | TDP1 (0.45) | ADRB2TDP1HTTSTAT3KMT2A | |
| SCHEMBL2082379 | 0.91 | TDP1 (0.45) | ADRB2TDP1HTTSTAT3KMT2A | |
| SCHEMBL9148485 | 0.89 | TDP1 (0.43) | ADRB2TDP1HTTSTAT3KMT2A | |
| SCHEMBL9149546 | 0.89 | TDP1 (0.43) | ADRB2TDP1HTTSTAT3KMT2A | |
| SCHEMBL9148480 | 0.89 | TDP1 (0.43) | ADRB2TDP1HTTSTAT3KMT2A | |
| SCHEMBL2080448 | 0.89 | CYP3A4 (0.49) | ADRB2TDP1HTTSTAT3KMT2A | |
| SCHEMBL2080449 | 0.89 | CYP3A4 (0.49) | ADRB2TDP1HTTSTAT3KMT2A | |
| SCHEMBL10365215 | 0.88 | STAT3 (0.55) | ADRB2TDP1HTTSTAT3KMT2A | |
| SCHEMBL2082038 | 0.87 | STAT3 (0.50) | ADRB2TDP1HTTSTAT3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |