Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149546 | 1.00 | TDP1 (0.43) | TDP1CYP3A4ADRB2HTTKMT2A | |
| SCHEMBL9148480 | 1.00 | TDP1 (0.43) | TDP1CYP3A4ADRB2HTTKMT2A | |
| SCHEMBL2079698 | 0.91 | TDP1 (0.44) | TDP1CYP3A4ADRB2HTTKMT2A | |
| SCHEMBL2079699 | 0.91 | TDP1 (0.44) | TDP1CYP3A4ADRB2HTTKMT2A | |
| SCHEMBL2082379 | 0.89 | TDP1 (0.45) | TDP1CYP3A4ADRB2HTTKMT2A | |
| SCHEMBL2082380 | 0.89 | TDP1 (0.45) | TDP1CYP3A4ADRB2HTTKMT2A | |
| SCHEMBL9145403 | 0.89 | ADRB2 (0.47) | TDP1CYP3A4ADRB2HTTKMT2A | |
| SCHEMBL9145398 | 0.89 | ADRB2 (0.47) | TDP1CYP3A4ADRB2HTTKMT2A | |
| SCHEMBL4466378 | 0.87 | ADRB2 (0.53) | TDP1ADRB2HTTKMT2ASTAT3 | |
| SCHEMBL3186793 | 0.87 | STAT3 (0.49) | ADRB2HTTKMT2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |