Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488978 | 0.92 | PPARD (0.50) | PPARDTSHRPOLBENPP2HDAC1 | |
| SCHEMBL21092115 | 0.85 | BTN3A1 (0.46) | BTN3A1LMNATSHRMAPTENPP2 | |
| SCHEMBL915441 | 0.85 | PPARD (0.44) | PPARDLMNAALDH1A1POLBKDM4E | |
| SCHEMBL3847237 | 0.83 | CYP2A6 (0.41) | PPARDBTN3A1ALDH1A1POLBKDM4E | |
| SCHEMBL915280 | 0.83 | FDPS (0.46) | PPARDLMNATSHRALDH1A1POLB | |
| SCHEMBL894078 | 0.83 | ALDH1A1 (0.44) | PPARDLMNAALDH1A1POLBKDM4E | |
| SCHEMBL12648165 | 0.83 | PPARD (0.42) | PPARDPOLBENPP2HDAC1PGK1 | |
| SCHEMBL914602 | 0.83 | PPARD (0.42) | PPARDBTN3A1ALDH1A1POLBKDM4E | |
| SCHEMBL5051393 | 0.83 | KMT2A (0.44) | PPARDBTN3A1LMNAPOLBENPP2 | |
| SCHEMBL915800 | 0.82 | TSHR (0.52) | PPARDTSHRPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500417-A | ANTIARTHRITIC | THE UPJOHN COMPANY (US) | 1996-03-19 | — | — | US | claimed |
| EP-0661978-A1 | ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1995-07-12 | — | — | EP | claimed |
| WO-1994007501-A1 | ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1994-04-14 | — | — | WO | claimed |
| US-7868126-B2 | Process for producing polyester, polyester produced using said process, and polyester molded product | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2011-01-11 | — | — | US | disclosed |
| EP-1842868-B1 | PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT | TOYO BOSEKI (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20090082529-A1 | Polyester, Process for Producing Polyester, and Polyester Molded Article | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2009-03-26 | — | — | US | disclosed |
| US-20080249280-A1 | Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2008-10-09 | — | — | US | disclosed |
| EP-1932867-A1 | POLYESTER, PROCESS FOR PRODUCTION OF POLYESTER, AND POLYESTER MOLDED ARTICLE | Toyo Boseki Kabushiki Kasisha (JP) | 2008-06-18 | — | — | EP | disclosed |