Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720160 | 1.00 | SIRT6 (0.46) | SIRT6LMNAMEN1KMT2AMAPT | |
| SCHEMBL9145647 | 1.00 | SIRT6 (0.46) | SIRT6LMNAMEN1KMT2AMAPT | |
| SCHEMBL29581173 | 0.88 | MEN1 (0.48) | SIRT6LMNAMEN1KMT2AMAPT | |
| SCHEMBL10510829 | 0.82 | POLB (0.47) | SIRT6MEN1KMT2AMAPTPOLB | |
| SCHEMBL1890695 | 0.81 | MEN1 (0.42) | SIRT6LMNAMEN1KMT2AMAPT | |
| SCHEMBL2392194 | 0.81 | SIRT6 (0.40) | SIRT6LMNAMEN1KMT2AMAPT | |
| SCHEMBL1894425 | 0.81 | MEN1 (0.42) | SIRT6LMNAMEN1KMT2AMAPT | |
| SCHEMBL3411641 | 0.80 | ALDH1A1 (0.45) | LMNAMAPTALDH1A1 | |
| SCHEMBL2718838 | 0.79 | DRD3 (0.42) | SIRT6MEN1KMT2AMAPTPOLB | |
| SCHEMBL30912607 | 0.79 | ALDH1A1 (0.51) | LMNAMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478939-A | Muscarinic agents | AMERICAN CYANAMID COMPANY (US) | 1995-12-26 | — | — | US | disclosed |