Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | UBE2N | P61088 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45682 | 0.84 | KDM4E (0.75) | KDM4EUBE2NATMALDH1A1TSHR | |
| SCHEMBL3265430 | 0.83 | CYP1B1 (0.62) | KDM4EUBE2NATMALDH1A1TSHR | |
| SCHEMBL18121471 | 0.82 | KDM4E (0.78) | KDM4EUBE2NATMALDH1A1TSHR | |
| SCHEMBL10660288 | 0.82 | KMT2A (0.63) | ALDH1A1CYP1B1GAAMEN1MAPT | |
| SCHEMBL11013871 | 0.82 | CA1 (0.56) | KDM4EUBE2NATMALDH1A1TSHR | |
| SCHEMBL9145775 | 0.79 | KDM4E (0.61) | KDM4EUBE2NATMALDH1A1TSHR | |
| SCHEMBL9142852 | 0.78 | ALDH1A1 (0.62) | KDM4EUBE2NATMALDH1A1TSHR | |
| SCHEMBL9144515 | 0.78 | ALDH1A1 (0.54) | KDM4EUBE2NATMALDH1A1TSHR | |
| SCHEMBL16862969 | 0.78 | KDM4E (0.67) | KDM4EUBE2NATMALDH1A1CYP1B1 | |
| SCHEMBL22258208 | 0.77 | KDM4E (0.70) | KDM4EUBE2NATMALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401756-A | Benzamide platelet activating factor antagonists | MITSUBISHI KASEI CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5304556-A | Platelet activating factor antagonists | MITSUBISHI KASEI CORPORATION (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0548934-A1 | Benzamide derivatives | Mitsubishi Chemical Corporation (JP) | 1993-06-30 | — | — | EP | disclosed |