Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | UBE2N | P61088 | 1/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.64 |
| ▸ | NAMPT | P43490 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CCR6 | P51684 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18121471 | 0.88 | KDM4E (0.78) | KDM4EUBE2NATMCYP1B1NAMPT | |
| SCHEMBL16862969 | 0.84 | KDM4E (0.67) | KDM4EUBE2NATMCYP1B1NAMPT | |
| SCHEMBL9145698 | 0.84 | KDM4E (0.59) | KDM4EUBE2NATMCYP1B1KMT2A | |
| SCHEMBL3265430 | 0.84 | CYP1B1 (0.62) | KDM4EUBE2NATMCYP1B1KMT2A | |
| SCHEMBL22258208 | 0.83 | KDM4E (0.70) | KDM4EUBE2NATMCYP1B1KMT2A | |
| SCHEMBL4625203 | 0.83 | CES1 (0.69) | KDM4EUBE2NATMCYP1B1HTT | |
| SCHEMBL14971246 | 0.81 | MEN1 (0.74) | KDM4EUBE2NATMNAMPTKMT2A | |
| SCHEMBL30596967 | 0.81 | MEN1 (0.74) | KDM4EUBE2NATMNAMPTKMT2A | |
| SCHEMBL9144515 | 0.81 | ALDH1A1 (0.54) | KDM4EUBE2NATMCYP1B1KMT2A | |
| SCHEMBL9142852 | 0.81 | ALDH1A1 (0.62) | KDM4EUBE2NATMNAMPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002913-A1 | PROCESS OF FORMING A CYCLIC IMIDE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-05 | — | — | WO | disclosed |
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | KDM4E 1573/4885UBE2N 4417/4885ATM 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.