Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146495 | 0.83 | NMT1 (0.62) | LMNAPOLBSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9144209 | 0.80 | KDM4E (0.53) | KDM4ELMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL9144138 | 0.80 | NMT1 (0.54) | KDM4ELMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL9142199 | 0.77 | L3MBTL1 (0.48) | KDM4EPOLBHTTSMN1; SMN2GAA | |
| SCHEMBL9587727 | 0.76 | POLB (0.74) | KDM4ELMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL29429164 | 0.76 | POLB (0.74) | KDM4ELMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL9144157 | 0.71 | NMT1 (0.60) | LMNAMEN1KMT2ANMT1 | |
| SCHEMBL3011861 | 0.69 | MEN1 (0.51) | KDM4ELMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL9148528 | 0.69 | L3MBTL1 (0.57) | KDM4ELMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL26688411 | 0.69 | KDM4E (0.55) | KDM4ELMNAPOLBSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424329-A | Administering an antiinflammatory agent to prevent leukocytes bonding to vascular endothelium, treating rheumatoid arthritis , asthma, psoriasis and AIDS | WARNER-LAMBERT COMPANY (US) | 1995-06-13 | — | — | US | disclosed |