Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.45 |
| ▸ | TUBB | P07437 | 2/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9144162 | 0.88 | SMN1; SMN2 (0.43) | L3MBTL1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL9141429 | 0.86 | L3MBTL1 (0.51) | L3MBTL1PABPC1EIF4HTUBB4ATUBB | |
| SCHEMBL5659192 | 0.79 | L3MBTL1 (0.55) | L3MBTL1PABPC1EIF4HTUBB4ATUBB | |
| SCHEMBL9537227 | 0.79 | L3MBTL1 (0.49) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9146147 | 0.77 | KDM4E (0.53) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL9142952 | 0.77 | L3MBTL1 (0.47) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9540898 | 0.75 | KDM4E (0.57) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL6456184 | 0.74 | KDM4E (0.49) | L3MBTL1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11530508 | 0.73 | KDM4E (0.68) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9146495 | 0.73 | NMT1 (0.62) | L3MBTL1SMN1; SMN2MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424329-A | Administering an antiinflammatory agent to prevent leukocytes bonding to vascular endothelium, treating rheumatoid arthritis , asthma, psoriasis and AIDS | WARNER-LAMBERT COMPANY (US) | 1995-06-13 | — | — | US | disclosed |