Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652584 | 0.86 | PLK1 (0.43) | PLK1PLK3SMN1; SMN2CA12CA1 | |
| SCHEMBL8654580 | 0.84 | HTT (0.51) | PLK1PLK3SMN1; SMN2CA12CA1 | |
| SCHEMBL8655078 | 0.84 | PLK1 (0.51) | PLK1PLK3SMN1; SMN2CA12CA1 | |
| SCHEMBL8653008 | 0.82 | SMN1; SMN2 (0.56) | PLK1PLK3SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9150540 | 0.81 | CA12 (0.44) | PLK1PLK3SMN1; SMN2CA12CA1 | |
| SCHEMBL8657531 | 0.81 | ALDH1A1 (0.56) | PLK1PLK3SMN1; SMN2CA12CA1 | |
| SCHEMBL8652685 | 0.81 | CA12 (0.56) | PLK1PLK3SMN1; SMN2CA12CA1 | |
| SCHEMBL9145624 | 0.81 | NPC1 (0.59) | PLK1PLK3SMN1; SMN2CA12CA1 | |
| SCHEMBL8652836 | 0.81 | PLK1 (0.57) | PLK1PLK3SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8658169 | 0.80 | PLK1 (0.59) | PLK1PLK3SMN1; SMN2ALDH1A1BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476957-A | Dye for heat sensitive recording | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-12-19 | — | — | US | disclosed |